Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761229 | 0.76 | GAA (0.53) | GAAKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL17775050 | 0.75 | CYP2C19 (0.56) | ALDH1A1LMNANR3C2 | |
| SCHEMBL17775053 | 0.74 | CYP1A2 (0.47) | LMNANR3C2 | |
| SCHEMBL8737631 | 0.74 | MAPT (0.52) | GAAKDM4EMAPTACHEALDH1A1 | |
| SCHEMBL24347717 | 0.73 | GAA (0.51) | GAAKDM4EMAPTACHEALDH1A1 | |
| SCHEMBL9150274 | 0.72 | MAPT (0.59) | GAAKDM4EMAPTACHEALDH1A1 | |
| SCHEMBL13814905 | 0.72 | MAPT (0.50) | GAAKDM4EMAPTACHEALDH1A1 | |
| SCHEMBL3583487 | 0.72 | CYP2C19 (0.61) | LMNANR3C2 | |
| SCHEMBL11211304 | 0.72 | CYP2C19 (0.61) | LMNANR3C2 | |
| SCHEMBL19185633 | 0.71 | GAA (0.49) | GAAKDM4EMAPTACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525111-B1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0525111-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS. | PFIZER (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | disclosed |