Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | MPC2 | O95563 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570304 | 0.99 | PPARG (0.54) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9205024 | 0.98 | PPARG (0.53) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9203600 | 0.97 | PPARG (0.53) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9197177 | 0.96 | PPARG (0.53) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9204965 | 0.96 | PPARG (0.56) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9203612 | 0.95 | PPARG (0.53) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL8565269 | 0.95 | PPARG (0.57) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9198339 | 0.94 | PPARG (0.53) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9204981 | 0.94 | PPARG (0.56) | PPARGCYP3A4HRH3RXRAFFAR1 | |
| SCHEMBL9200592 | 0.93 | PPARG (0.54) | PPARGCYP3A4HRH3RXRAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549365-B1 | Thiazolidine compounds, their preparation and their therapeutic uses | SANKYO CO (JP) | 1995-08-09 | — | — | EP | claimed |
| EP-0549365-A1 | Thiazolidine compounds, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0549365-B1 | Thiazolidine compounds, their preparation and their therapeutic uses | SANKYO CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0549365-A1 | Thiazolidine compounds, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |