Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209962 | 0.88 | GAA (0.52) | GAADHODHMEN1KMT2ACYP3A4 | |
| SCHEMBL1567868 | 0.74 | SMN1; SMN2 (0.44) | GAANPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL9201090 | 0.72 | HTT (0.39) | NPSR1ALDH1A1LMNAMAPTCYP2C19 | |
| SCHEMBL6311447 | 0.72 | HTT (0.40) | NPSR1LMNACYP2C19 | |
| SCHEMBL9203467 | 0.72 | HTT (0.46) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7474279 | 0.70 | KMT2A (0.51) | GAADHODHMEN1KMT2ACYP3A4 | |
| SCHEMBL2116283 | 0.69 | DHODH (0.57) | GAADHODHMEN1KMT2ACYP3A4 | |
| SCHEMBL23727393 | 0.67 | MEN1 (0.46) | GAADHODHMEN1KMT2ACYP3A4 | |
| SCHEMBL10862764 | 0.67 | MEN1 (0.71) | GAADHODHMEN1KMT2ACYP3A4 | |
| SCHEMBL10511749 | 0.66 | MEN1 (0.58) | GAADHODHMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390739-B1 | Substituted aminopyrroles as stabilisers in chlorinated polymers | CIBA GEIGY AG (CH) | 1995-08-09 | — | — | EP | disclosed |
| US-5155152-A | SUBSTITUTE AMINOPYRROLES AS STABILIZERS FOR CHLORINE-CONTAINING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |