Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206612 | 0.96 | SMN1; SMN2 (0.37) | SMN1; SMN2C5AR1HPGDKDM4ECYP1A2 | |
| SCHEMBL9074842 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL9077271 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL9506024 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL10828309 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10828311 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDALDH1A1HTTL3MBTL1 | |
| SCHEMBL10828297 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDKDM4ECYP1A2CYP2C19 | |
| SCHEMBL10829260 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL10832908 | 0.70 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4EGAAPSMB8 | |
| SCHEMBL9386160 | 0.70 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656891-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-06-14 | — | — | EP | claimed |
| WO-1994004509-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1994-03-03 | — | — | WO | claimed |
| EP-0656891-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994004509-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1994-03-03 | — | — | WO | disclosed |