SCHEMBL920689

SCHEMBL920689

COC(C)OC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5988257 0.90 TSHR (0.31)
SCHEMBL22299925 0.85 TSHR (0.38)
SCHEMBL2262906 0.80 TSHR (0.35)
SCHEMBL11334964 0.79 TSHR (0.31)
SCHEMBL984063 0.77 TSHR (0.36)
SCHEMBL392490 0.76 TSHR (0.50)
SCHEMBL8458788 0.76 TSHR (0.38)
SCHEMBL17489309 0.74
SCHEMBL4443065 0.74
SCHEMBL577005 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479820-B2 Pyridin-3-yl derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2025-11-25 US disclosed
US-20250215010-A1 DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS VASA THERAPEUTICS SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2025-07-03 US disclosed
CN-119923399-A Useful as matrix metalloproteinase inhibitors diazabicyclooctane derivatives of (a) 瓦萨治疗有限责任公司 2025-05-02 CN disclosed
CN-118786128-A Compounds and methods for treating viral infections 吉利德科学公司 2024-10-15 CN disclosed
CN-114026082-B Pyridin-3-yl derivatives 爱杜西亚药品有限公司 2024-06-07 CN disclosed
CN-117897386-A Benzopyran derivatives and uses thereof 斯帕克生物制药有限公司 2024-04-16 CN disclosed
EP-3762386-B1 ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF TEON THERAPEUTICS INC (US) 2024-01-24 EP disclosed
WO-2023057548-A1 CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2023-04-13 WO disclosed
CN-115819280-A Preparation method of cyflumetofen 天津均凯农业科技有限公司 2023-03-21 CN disclosed
US-20220251068-A1 PYRIDIN-3-YL DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2022-08-11 US disclosed
EP-0378930-B1 Cyclic urea derivative NIPPON PAINT CO LTD (JP) 1996-05-08 EP disclosed
US-5427588-A Oxidation hair dyes; 1-oxy- or aminocarbonyl or oxy- or aminothiocarbonylindololines L'OREAL (FR) 1995-06-27 US disclosed
US-5385985-A Cyclic urea derivative NIPPON PAINT CO., LTD. (JP) 1995-01-31 US disclosed
US-5268252-A Polyol with o-naphthoquinone-2-diazide-4-sulfonic acid HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-07 US disclosed
US-5214055-A Analgesics, psychological disorders, anxiolytic agents ADIR ET COMPAGNIE (FR) 1993-05-25 US disclosed
US-5189045-A Antiserotonine agent ADIR ET COMPAGNIE (FR) 1993-02-23 US disclosed
US-5017702-A 2,6-polyalkyl-4-piperidylamides, use thereof as stabilizers, in particular for plastics, and organic material containing same BASF AKTIENGESELLSCHAFT (DE) 1991-05-21 US disclosed
US-5015565-A Silver halide emulsion on a support with a cyan coupler AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
EP-0378930-A1 Cyclic urea derivative NIPPON PAINT CO., LTD. (JP) 1990-07-25 EP disclosed
US-4160866-A CROSSLINKERS FOR NATURAL AND SYNTHETIC RUBBERS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-10 US disclosed