Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388640 | 0.84 | TACR1 (0.81) | TACR1SLC6A4 | |
| SCHEMBL1388742 | 0.84 | TACR1 (0.77) | TACR1SLC6A4 | |
| SCHEMBL8104677 | 0.82 | TACR1 (0.77) | TACR1SLC6A4 | |
| SCHEMBL1388343 | 0.81 | TACR1 (0.75) | TACR1SLC6A4 | |
| SCHEMBL9210141 | 0.80 | TACR1 (0.71) | TACR1SLC6A4 | |
| SCHEMBL1388346 | 0.79 | TACR1 (0.71) | TACR1SLC6A4 | |
| SCHEMBL1388321 | 0.79 | TACR1 (0.75) | TACR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL8114619 | 0.79 | TACR1 (0.69) | TACR1SLC6A4 | |
| SCHEMBL8114814 | 0.79 | TACR1 (1.00) | TACR1SLC6A4 | |
| SCHEMBL1388594 | 0.79 | TACR1 (1.00) | TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666856-A1 | 4-ARYLMETHYLOXYMETHYL PIPERIDINES AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1995-08-16 | — | — | EP | claimed |
| EP-0666856-A1 | 4-ARYLMETHYLOXYMETHYL PIPERIDINES AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1995-08-16 | — | — | EP | disclosed |