Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | BCHE | P06276 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.71 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.67 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207320 | 1.00 | MAPT (0.74) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL7103789 | 0.86 | MAPT (0.74) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL9202149 | 0.85 | MAPT (0.55) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL9204167 | 0.85 | MAPT (0.53) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL9202156 | 0.85 | MAPT (0.55) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL9203900 | 0.85 | MAPT (0.73) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL9204172 | 0.85 | MAPT (0.53) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL9203891 | 0.85 | MAPT (0.73) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL1723179 | 0.85 | MAPT (1.00) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL1723180 | 0.85 | MAPT (1.00) | MAPTNPC1LMNARAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |