SCHEMBL92089

SCHEMBL92089

Cc1ccc2c(c1S(=O)(=O)O)SC(c1ccc(/N=N/c3c(O)c(C(=O)O)cc4ccccc34)cc1)N2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 3/20 0.50
POLB P06746 3/20 0.50
USP2 O75604 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MPL P40238 2/20 0.48
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 2/20 0.47
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
IDO1 P14902 1/20 0.46
MAPK1 P28482 1/20 0.46
RECQL P46063 1/20 0.46
CASP6 P55212 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MITF O75030 1/20 0.46
CYP2D6 P10635 1/20 0.44
APP P05067 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92012 0.89 NQO2 (0.40) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL9029942 0.75 MPL (0.67) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL12955195 0.75 MPL (0.67) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL92098 0.73 KMT2A (0.80) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL5351787 0.72 MEN1 (0.71) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL5351789 0.72 MEN1 (0.71) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL343952 0.71 MEN1 (0.78) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL29582683 0.71 MEN1 (0.78) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL343951 0.71 MEN1 (0.78) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL29355358 0.70 MEN1 (0.76) MEN1KMT2AMAPTPOLBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2146230-B1 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT FINANCE BVI LTD (VG) 2012-09-12 EP disclosed
EP-2145926-B1 PR 254 pigment preparation for use in colour filters CLARIANT FINANCE BVI LTD (VG) 2012-05-30 EP disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
EP-2205682-B1 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE BVI LTD (VG) 2011-03-09 EP disclosed
US-7892344-B2 P.R. 254 pigment preparation for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2011-02-22 US disclosed
US-7892344-B2 P.R. 254 pigment preparation for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2011-02-22 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
EP-2145926-A2 PR 254 pigment preparation for use in colour filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-20 EP disclosed
EP-2146230-A2 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-20 EP disclosed
US-20100006009-A1 P.R. 254 Pigment Preparation for use in Color Filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-14 US disclosed
US-20100006009-A1 P.R. 254 Pigment Preparation for use in Color Filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-14 US disclosed
WO-2009049736-A2 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE (BVI) LIMITED (VG) 2009-04-23 WO disclosed