Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH4 | P08319 | 2/20 | 0.38 |
| ▸ | ADH7 | P40394 | 2/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541689 | 1.00 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL14625028 | 1.00 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL9204346 | 1.00 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL27800763 | 1.00 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL9206251 | 1.00 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL24353239 | 1.00 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL11699658 | 1.00 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 | |
| SCHEMBL117250 | 0.95 | EPHX1 (0.42) | EPHX1TSHRLMNACNR1ADRA1A | |
| SCHEMBL9213526 | 0.95 | EPHX1 (0.42) | EPHX1TSHRLMNACNR1ADRA1A | |
| SCHEMBL9212478 | 0.95 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |