SCHEMBL9208932

SCHEMBL9208932

c1ccc(-c2ccccc2-c2cc(Oc3ccc(-c4ccccc4)c(-c4ccccc4-c4ccccc4)c3)ccc2-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.48
MAOA P21397 4/20 0.47
MAOB P27338 4/20 0.47
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
MEN1 O00255 1/20 0.44
APAF1 O14727 1/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
XBP1 P17861 1/20 0.44
PTBP1 P26599 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
GALK1 P51570 1/20 0.44
BLM P54132 1/20 0.44
SMAD3 P84022 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9730496 0.92 GSTP1 (0.55) GSTP1MAOAMAOBNCOA1NCOA3
SCHEMBL13445888 0.91 GSTP1 (0.52) GSTP1MAOAMAOBNCOA1NCOA3
SCHEMBL29251915 0.89 MAOB (0.50) GSTP1MAOAMAOBMEN1LMNA
SCHEMBL9220631 0.85 GSTP1 (0.62) GSTP1MAOAMAOBNCOA1NCOA3
SCHEMBL9220634 0.82 GSTP1 (0.58) GSTP1MAOAMAOBNCOA1NCOA3
SCHEMBL11751812 0.81 GSTP1 (0.61) GSTP1MAOANCOA1NCOA3NPC1
SCHEMBL11753055 0.80 GSTP1 (0.55) GSTP1MAOAMAOBNCOA1NCOA3
SCHEMBL3555602 0.79 NCOA1 (0.59) GSTP1MAOAMAOBNCOA1NCOA3
SCHEMBL3557154 0.79 NCOA1 (0.59) GSTP1MAOAMAOBNCOA1NCOA3
SCHEMBL27601570 0.78 GSTP1 (0.53) GSTP1MAOAMAOBMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5464569-A In situ formation of alkali metal oxalates in polyphenylene ether basestock MONSANTO COMPANY (US) 1995-11-07 US disclosed
US-5439614-A Colloidal dispersion of aromatic ether and oxidation inhibiting amount of alkali metal salt of oxalic acid MONSANTO COMPANY (US) 1995-08-08 US disclosed