Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597584 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9201304 | 0.86 | CYSLTR1 (0.54) | CYSLTR2CYSLTR1 | |
| SCHEMBL9201307 | 0.86 | CYSLTR1 (0.54) | CYSLTR2CYSLTR1 | |
| SCHEMBL9202703 | 0.81 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1 | |
| SCHEMBL9202710 | 0.81 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1 | |
| SCHEMBL9202187 | 0.81 | F2 (0.38) | — | |
| SCHEMBL9208589 | 0.80 | CYSLTR1 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL9208597 | 0.80 | CYSLTR1 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL8500070 | 0.78 | CYSLTR1 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL8500066 | 0.78 | CYSLTR1 (0.55) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399818-B1 | Diarylstyrylquinoline diacids | MERCK FROSST CANADA INC (CA) | 1995-08-16 | — | — | EP | disclosed |
| US-5204358-A | Antiallergens; antiinflammatory agents; treatment of asthma, rhinitis, bronchitis and skin diseases | MERCK FROSST CANADA, INC. (CA) | 1993-04-20 | — | — | US | disclosed |
| US-5104882-A | Leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1992-04-14 | — | — | US | disclosed |
| EP-0318093-A2 | Diarylquinoline diacids and their use as medicaments | MERCK FROSST CANADA INC. (CA) | 1989-05-31 | — | — | EP | disclosed |