Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218933 | 0.94 | NPSR1 (0.49) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9209461 | 0.94 | NPSR1 (0.48) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9545337 | 0.93 | NPSR1 (0.47) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9216821 | 0.91 | NPSR1 (0.55) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9220306 | 0.91 | NPSR1 (0.55) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9544722 | 0.91 | NPSR1 (0.46) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9218210 | 0.90 | NPSR1 (0.47) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9219939 | 0.90 | NPSR1 (0.45) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9217821 | 0.90 | NPSR1 (0.45) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9213149 | 0.90 | NPSR1 (0.44) | NPSR1CYP1A2CYP2C19CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | claimed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | claimed |
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | disclosed |