Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9212656 | 0.98 | MAPT (0.47) | MAPTMEN1KMT2ALOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10560690 | 0.88 | MAPT (0.45) | MAPTMEN1KMT2ALOXL2ALDH1A1 | |
| SCHEMBL4907801 | 0.82 | MAPT (0.46) | MAPTMEN1KMT2ALOXL2ALDH1A1 | |
| SCHEMBL5280249 | 0.81 | MAPT (0.57) | MAPTMEN1KMT2ALOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5654081 | 0.80 | MAPT (0.55) | MAPTMEN1KMT2ALOXL2ALDH1A1 | |
| SCHEMBL6103872 | 0.79 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL14113990 | 0.79 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL223594 | 0.78 | MEN1 (0.59) | MAPTMEN1KMT2ALOXL2ALDH1A1 | |
| SCHEMBL4900236 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2ALOXL2ALDH1A1 | |
| SCHEMBL18690302 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2ALOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445813-B1 | 7-(Diphenylmethyl)oxy-9a-methoxymitosane and the preparation and use thereof | BRISTOL MYERS SQUIBB CO (US) | 1995-08-02 | — | — | EP | disclosed |
| US-5352798-A | Intermediates for mitomycins; antitumor agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5175303-A | Antitumor agents formed by reaction of diazodiphenylmethane and mitomycin C | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5075454-A | Chemical intermediate, antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0445813-A1 | 7-(Diphenylmethyl)oxy-9a-methoxymitosane and the preparation and use thereof | Bristol-Myers Squibb Company (US) | 1991-09-11 | — | — | EP | disclosed |