Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212201 | 1.00 | S1PR3 (0.47) | S1PR3EPHX2KMT2ACYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL9211779 | 0.99 | S1PR3 (0.46) | S1PR3EPHX2KMT2ACYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL9211777 | 0.99 | S1PR3 (0.46) | S1PR3EPHX2KMT2ACYP2C19CYP2C9 | |
| SCHEMBL9208909 | 0.84 | CYP2C9 (0.42) | EPHX2KMT2ACYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9213965 | 0.84 | CYP2C9 (0.42) | EPHX2KMT2ACYP2C19CYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL9217997 | 0.83 | CYP2C9 (0.41) | EPHX2KMT2ACYP2C19CYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL9218004 | 0.83 | CYP2C9 (0.41) | EPHX2KMT2ACYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9211715 | 0.83 | EPHX2 (0.46) | EPHX2KMT2ACYP2C19CYP2C9CYP3A4 | |
| SCHEMBL9211713 | 0.83 | EPHX2 (0.46) | EPHX2KMT2ACYP2C19CYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL9218712 | 0.82 | EPHX2 (0.45) | EPHX2CYP2C19CYP2C9CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | claimed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | claimed |
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |