Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202719 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9214782 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9207554 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9211997 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9204519 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9202980 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9213238 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9209531 | 0.98 | TSHR (0.33) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9210550 | 0.95 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9211485 | 0.95 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |