Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.75 |
| ▸ | CNR2 | P34972 | 10/20 | 0.75 |
| ▸ | CNR1 | P21554 | 8/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212425 | 1.00 | TRPV1 (0.75) | TRPV1CNR2CNR1MEN1ALDH1A1 | |
| SCHEMBL9204690 | 1.00 | TRPV1 (0.75) | TRPV1CNR2CNR1MEN1ALDH1A1 | |
| SCHEMBL9204695 | 1.00 | TRPV1 (0.75) | TRPV1CNR2CNR1MEN1ALDH1A1 | |
| SCHEMBL9209602 | 0.96 | CNR2 (0.70) | TRPV1CNR2CNR1MEN1ALDH1A1 | |
| SCHEMBL9209547 | 0.92 | TRPV1 (0.71) | TRPV1CNR2CNR1 | |
| SCHEMBL4135884 | 0.92 | TRPV1 (0.71) | TRPV1CNR2CNR1 | |
| SCHEMBL4133180 | 0.92 | TRPV1 (0.71) | TRPV1CNR2CNR1 | |
| SCHEMBL30526488 | 0.92 | TRPV1 (0.71) | TRPV1CNR2CNR1 | |
| SCHEMBL30526485 | 0.92 | TRPV1 (0.71) | TRPV1CNR2CNR1 | |
| SCHEMBL4133182 | 0.92 | TRPV1 (0.71) | TRPV1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |