Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213385 | 0.97 | EPHX1 (0.33) | EPHX1SHBGTP53KDM4EGMNN | |
| SCHEMBL9206468 | 0.86 | EPHX1 (0.34) | EPHX1SHBGTP53KDM4EGMNN | |
| SCHEMBL9204416 | 0.84 | EPHX1 (0.33) | EPHX1SHBGTP53KDM4EGMNN | |
| SCHEMBL9213422 | 0.83 | EPHX1 (0.31) | EPHX1SHBG | |
| SCHEMBL9214843 | 0.82 | EPHX1 (0.32) | EPHX1SHBGTP53 | |
| SCHEMBL9209420 | 0.82 | EPHX1 (0.32) | EPHX1SHBGTP53 | |
| SCHEMBL9213058 | 0.82 | EPHX1 (0.32) | EPHX1SHBGTP53 | |
| SCHEMBL9213833 | 0.81 | EPHX1 (0.30) | EPHX1SHBG | |
| SCHEMBL9211700 | 0.79 | — | — | |
| SCHEMBL9202932 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |