Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562231 | 1.00 | KMT2A (0.40) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL10551891 | 0.94 | KMT2A (0.37) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL30843044 | 0.88 | MEN1 (0.40) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL4567521 | 0.88 | MEN1 (0.40) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL3695378 | 0.88 | MEN1 (0.40) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL9561731 | 0.88 | MEN1 (0.40) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL17350379 | 0.88 | KMT2A (0.36) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL17350817 | 0.86 | KMT2A (0.41) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL12889528 | 0.85 | MEN1 (0.44) | KMT2AMEN1NPSR1LMNAMAPT | |
| SCHEMBL10544905 | 0.82 | NPSR1 (0.42) | KMT2AMEN1NPSR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457090-B1 | Process for the preparation of 3-amino-2 (het)aroyl-acrylic acid derivatives | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5182401-A | Bactericide intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-26 | — | — | US | disclosed |
| EP-0457090-A2 | Process for the preparation of 3-amino-2 (het)aroyl-acrylic acid derivatives | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |