Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202848 | 0.91 | TSHR (0.61) | TSHRALDH1A1TRPA1 | |
| SCHEMBL7153127 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL2848855 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL11900766 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL8746863 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL23539923 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL13280495 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL22164116 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL22322880 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL1548257 | 0.87 | TSHR (1.00) | TSHRALDH1A1THRBFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |