SCHEMBL9214309

CN1C(=O)CC(=O)[C@@]2(C)C1CC[C@@H]1[C@H]2CC[C@]2(C)C(C(=O)N(C(=S)NC(C)(C)C)C(C)(C)C)CC[C@@H]12

nearest known ligand 0.64

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	SRD5A2	P31213	4/20	0.64

▸	SRD5A1	P18405	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9214304	1.00	SRD5A2 (0.64)	SRD5A2SRD5A1
SCHEMBL9207188	0.87	SRD5A2 (0.83)	SRD5A2SRD5A1
SCHEMBL9207192	0.87	SRD5A2 (0.83)	SRD5A2SRD5A1
SCHEMBL9212335	0.81	SRD5A2 (0.62)	SRD5A2SRD5A1
SCHEMBL9212331	0.81	SRD5A2 (0.62)	SRD5A2SRD5A1
SCHEMBL9207700	0.78	SRD5A2 (1.00)	SRD5A2SRD5A1
SCHEMBL9207708	0.78	SRD5A2 (1.00)	SRD5A2SRD5A1
SCHEMBL9207751	0.77	SRD5A2 (0.73)	SRD5A2SRD5A1
SCHEMBL9207747	0.77	SRD5A2 (0.73)	SRD5A2SRD5A1
SCHEMBL9205325	0.76	SRD5A2 (0.64)	SRD5A2SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0468012-B1	17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION	PHARMACIA SPA (IT)	1995-09-20	—	—	EP	disclosed