⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376992 | 0.80 | — | — | |
| SCHEMBL2497821 | 0.80 | — | — | |
| SCHEMBL4891822 | 0.77 | NPSR1 (0.41) | — | |
| SCHEMBL3725173 | 0.72 | — | — | |
| SCHEMBL3721440 | 0.72 | — | — | |
| SCHEMBL28805320 | 0.72 | — | — | |
| SCHEMBL28719318 | 0.72 | — | — | |
| SCHEMBL7768517 | 0.72 | — | — | |
| SCHEMBL27823567 | 0.71 | — | — | |
| SCHEMBL10991042 | 0.70 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531091-B1 | Biodegradable copolyester of 4-hydroxy proline and pharmaceutical composition containing the same | TEIJIN LTD (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-5395916-A | Glycolic acid derivative comonomer; time-release agents; drug delivery; polylactones | TEIJIN LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0531091-A1 | Biodegradable copolyester of 4-hydroxy proline and pharmaceutical composition containing the same | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |