Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.59 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575732 | 0.85 | ASAH1 (0.54) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL28217435 | 0.85 | ASAH1 (0.66) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL6569302 | 0.84 | LPAR3 (0.58) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL6570288 | 0.84 | LPAR3 (0.58) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL6568705 | 0.84 | LPAR3 (0.58) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL6569341 | 0.84 | LPAR3 (0.58) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL6570354 | 0.84 | LPAR3 (0.58) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL7618294 | 0.84 | LPAR3 (0.58) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL6569383 | 0.84 | LPAR3 (0.58) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL6568499 | 0.84 | ASAH1 (0.55) | ASAH1ALDH1A1ACER2SMPD2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499521-B1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0499521-A1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-08-19 | — | — | EP | disclosed |