Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.32 |
| ▸ | PSMB3 | P49720 | 3/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.32 |
| ▸ | PSMA6 | P60900 | 3/20 | 0.32 |
| ▸ | PSMA8 | Q8TAA3 | 3/20 | 0.32 |
| ▸ | PSMB7 | Q99436 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208871 | 1.00 | TSHR (0.32) | TSHRPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7186558 | 0.93 | — | — | |
| SCHEMBL9209670 | 0.89 | TSHR (0.34) | TSHR | |
| SCHEMBL9208174 | 0.89 | TSHR (0.34) | TSHR | |
| SCHEMBL9207932 | 0.89 | TSHR (0.34) | TSHR | |
| SCHEMBL7992617 | 0.87 | — | — | |
| SCHEMBL7992448 | 0.82 | NPC1 (0.32) | — | |
| SCHEMBL27515454 | 0.81 | MEN1 (0.34) | — | |
| SCHEMBL7998016 | 0.80 | NPC1 (0.31) | — | |
| SCHEMBL7991221 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |