Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612514 | 1.00 | ELANE (0.46) | ELANEPLCG1RAB9ATDP1HTR2A | |
| SCHEMBL9216219 | 1.00 | ELANE (0.46) | ELANEPLCG1RAB9ATDP1HTR2A | |
| SCHEMBL10862718 | 0.87 | PLCG1 (0.40) | ELANEPLCG1RAB9ATDP1HTR2A | |
| SCHEMBL10862713 | 0.87 | PLCG1 (0.40) | ELANEPLCG1RAB9ATDP1HTR2A | |
| SCHEMBL10865984 | 0.87 | PLCG1 (0.40) | ELANEPLCG1RAB9ATDP1HTR2A | |
| SCHEMBL10757693 | 0.86 | ELANE (0.42) | ELANEPLCG1RAB9AHTR2AHTT | |
| SCHEMBL10757699 | 0.86 | ELANE (0.42) | ELANEPLCG1RAB9AHTR2AHTT | |
| SCHEMBL10757697 | 0.86 | ELANE (0.42) | ELANEPLCG1RAB9AHTR2AHTT | |
| SCHEMBL9025689 | 0.86 | ELANE (0.39) | ELANEPLCG1RAB9ATDP1L3MBTL1 | |
| SCHEMBL10759797 | 0.85 | ELANE (0.42) | ELANEPLCG1RAB9AHTR2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424422-A | Beta-lactams and their production | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5310897-A | Beta-lactams and their production | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0188816-B1 | NOVEL BETA-LACTAMS AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-10-17 | — | — | EP | disclosed |
| EP-0188816-A1 | Novel beta-lactams and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |