SCHEMBL9216249

SCHEMBL9216249

CCCCCCCCOc1cccc2c(C(=O)O)cccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.66
CNR2 P34972 4/20 0.66
CYP2C9 P11712 1/20 0.64
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
NR1I2 O75469 1/20 0.58
LMNA P02545 1/20 0.58
CHRM2 P08172 1/20 0.58
CYP3A4 P08684 1/20 0.58
ADRA2A P08913 1/20 0.58
MAPT P10636 1/20 0.58
OPRK1 P41145 1/20 0.58
HTR2B P41595 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
THRA P10827 1/20 0.56
THRB P10828 1/20 0.56
PTPN11 Q06124 5/20 0.55
HTT P42858 1/20 0.52
PTPN1 P18031 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL249271 0.90 CNR2 (0.69) CNR1CNR2CYP2C9MEN1KMT2A
SCHEMBL10960208 0.89 CNR2 (0.63) CNR1CNR2CYP2C9MEN1KMT2A
Triphenylene SCHEMBL7588535 0.87 KMT2A (0.68) CNR1CNR2CYP2C9MEN1KMT2A
SCHEMBL27624634 0.85 CNR2 (0.68) CNR1CNR2CYP2C9MEN1KMT2A
Naphthoic Acid SCHEMBL27493013 0.85 CNR2 (0.91) CNR1CNR2CYP2C9MEN1KMT2A
SCHEMBL18141371 0.84 KMT2A (0.74) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL1274781 0.84 KMT2A (0.74) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL3665313 0.84 KMT2A (0.74) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL112985 0.84 KMT2A (0.74) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL6575990 0.84 KMT2A (0.74) MEN1KMT2ANR1I2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0405974-B1 Holographic operating optical apparatus SEIKO INSTR INC (JP) 1995-11-29 EP disclosed
EP-0518449-B1 Optical interconnection apparatus SEIKO INSTR INC (JP) 1995-11-02 EP disclosed
EP-0518449-A1 Optical interconnection apparatus SEIKO INSTRUMENTS INC. (JP) 1992-12-16 EP disclosed
US-5132811-A Holographic operating optical apparatus SEIKO INSTRUMENTS INC. (JP) 1992-07-21 US disclosed
EP-0405974-A2 Holographic operating optical apparatus SEIKO INSTRUMENTS INC. (JP) 1991-01-02 EP disclosed