SCHEMBL9217175

SCHEMBL9217175

CCC(C)NC(=O)c1ncccc1C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ADRA1A P35348 1/20 0.46
POLB P06746 1/20 0.44
THRB P10828 1/20 0.44
RAB9A P51151 1/20 0.43
P2RX7 Q99572 1/20 0.43
DYRK1A Q13627 1/20 0.42
MAPT P10636 1/20 0.42
ATM Q13315 1/20 0.42
NAMPT P43490 1/20 0.42
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7451831 0.85 KDM4E (0.46) KDM4EALDH1A1HSD17B10HPGDHTT
SCHEMBL7452205 0.80 KDM4E (0.52) KMT2AKDM4EALDH1A1HSD17B10HPGD
SCHEMBL27642674 0.79 MEN1 (0.71) MEN1KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL15204566 0.78 MEN1 (0.60) MEN1KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL7452418 0.77 KDM4E (0.49) KDM4EALDH1A1HSD17B10HPGDHTT
SCHEMBL9213267 0.77 KDM4E (0.61) MEN1KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL9589369 0.77 TP53 (0.42) MEN1KMT2AALDH1A1HTTL3MBTL1
SCHEMBL5902495 0.76 PARP1 (0.50) KDM4EALDH1A1HSD17B10HPGDHTT
SCHEMBL9206936 0.75 HTT (0.56) MEN1KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL14355563 0.75 KDM4E (0.61) MEN1KMT2AKDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0422456-B1 Pyridine derivatives and their use in combating unwanted plant growth BASF AG (DE) 1995-05-03 EP claimed