SCHEMBL9218151

SCHEMBL9218151

N[C@@H](CC(Cc1ccccc1)(Cc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
PTGS1 P23219 1/20 0.55
XIAP P98170 1/20 0.55
SLC7A5 Q01650 1/20 0.55
KIF11 P52732 14/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
SLC1A3 P43003 2/20 0.47
SLC1A2 P43004 2/20 0.47
SLC1A1 P43005 2/20 0.47
GRIK1 P39086 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13524317 0.81 ALPI (0.53) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1039559 0.81 ALPI (0.53) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL560236 0.81 ALPI (0.53) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27918415 0.80 SMN1; SMN2 (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1835148 0.79 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL4398295 0.79 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1835145 0.79 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL4398300 0.79 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL2344672 0.78 ALPI (0.53) ALPIPKMPTGS1XIAPSLC7A5
Bromide SCHEMBL2192294 0.78 ALPI (0.53) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015069766-A1 DUPA-INDENOISOQUINOLINE CONJUGATES PURDUE RESEARCH FOUNDATION (US) 2015-05-14 WO disclosed
WO-1995003067-A1 PHARMACEUTICAL WITH IMMUNOMODULATING ACTIVITY KHAVINSON VLADIMIR KHATSKELEVI (RU) 1995-02-02 WO disclosed