SCHEMBL9218784

SCHEMBL9218784

Nc1ccc(C(=O)CC(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
KDM4E B2RXH2 2/20 0.57
HIF1A Q16665 2/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
SLC22A8 Q8TCC7 1/20 0.57
KMT2A Q03164 5/20 0.51
MEN1 O00255 4/20 0.51
CYP3A4 P08684 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 1/20 0.50
CES1 P23141 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
APEX1 P27695 1/20 0.47
RAB9A P51151 4/20 0.45
NPC1 O15118 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11365527 0.88 MAPT (0.56) MAPTKDM4EHIF1ASLC22A6SLC22A8
SCHEMBL29249309 0.88 KMT2A (0.62) MAPTKDM4EHIF1AKMT2AMEN1
SCHEMBL28417483 0.84 MEN1 (0.74) MAPTKDM4EHIF1ASLC22A6SLC22A8
SCHEMBL9352579 0.81 TSHR (0.60) MAPTKDM4EKMT2AMEN1CYP3A4
SCHEMBL28360725 0.81 KDM4E (0.66) MAPTKDM4EHIF1ASLC22A6SLC22A8
SCHEMBL11150129 0.80 MEN1 (0.50) MAPTKDM4EHIF1ASLC22A6SLC22A8
SCHEMBL2652443 0.80 NR4A2 (0.65) MAPTKDM4EHIF1ASLC22A6SLC22A8
Hydrazine SCHEMBL28863919 0.79 CYP3A4 (0.73) MAPTKDM4EHIF1AKMT2AMEN1
SCHEMBL2715371 0.79 PTPN1 (0.58) MAPTKDM4EHIF1AKMT2AMEN1
Hydrochloric Acid SCHEMBL9462713 0.78 NR4A2 (0.63) MAPTKDM4EHIF1ASLC22A6SLC22A8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102942695-B Polymer, glucose nano gel, glucose nano gel composition and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2014-03-26 CN claimed
CN-102942695-A Polymer, glucose nano gel, glucose nano gel composition and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2013-02-27 CN claimed
CN-108883394-B Chromatography matrix 思拓凡生物工艺研发有限公司 2022-05-10 CN disclosed
CN-107108526-A Bifunctional compounds and use for reducing uric acid levels R·P·小沃勒尔 2017-08-29 CN disclosed
CN-102942695-B Polymer, glucose nano gel, glucose nano gel composition and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2014-03-26 CN disclosed
CN-102942695-A Polymer, glucose nano gel, glucose nano gel composition and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2013-02-27 CN disclosed
US-5459026-A N-phosphonoalkylindole derivatives FUJI PHOTO FILM CO., LTD. (JP) 1995-10-17 US disclosed