Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025534 | 0.91 | MAPK1 (0.40) | MAPK1KMT2AALDH1A1ADORA2AADORA2B | |
| SCHEMBL9024643 | 0.88 | MAPK1 (0.40) | MAPK1KMT2AALDH1A1PKMTP53 | |
| SCHEMBL9026839 | 0.85 | MAPK1 (0.40) | MAPK1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9026849 | 0.84 | MAPK1 (0.37) | MAPK1KMT2AADORA2ALMNAPKM | |
| SCHEMBL9025289 | 0.84 | MAPK1 (0.38) | MAPK1KMT2AALDH1A1LMNAPKM | |
| SCHEMBL9025981 | 0.79 | MAPK1 (0.36) | MAPK1ALDH1A1LMNAPKMSMN1; SMN2 | |
| SCHEMBL9026244 | 0.79 | MAPT (0.39) | KMT2ATP53SMN1; SMN2NPC1MAPT | |
| SCHEMBL9026378 | 0.78 | KDM4E (0.38) | MAPK1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9025839 | 0.78 | PTGDR2 (0.39) | KMT2AALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL9026568 | 0.77 | MAPK1 (0.39) | MAPK1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |