Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599538 | 0.84 | PTGER1 (0.46) | PTGER1LMNACCR5HTT | |
| SCHEMBL2167179 | 0.82 | CHRM2 (0.51) | CHRM2CHRM1CHRM3ADRB2LMNA | |
| SCHEMBL723993 | 0.82 | CHRM2 (0.51) | CHRM2CHRM1CHRM3ADRB2LMNA | |
| SCHEMBL596294 | 0.82 | CHRM2 (0.51) | CHRM2CHRM1CHRM3ADRB2LMNA | |
| SCHEMBL27510678 | 0.79 | CHRM2 (0.53) | CHRM2CHRM1CHRM3ADRB2LMNA | |
| Cadaverine Tartrate SCHEMBL11317075 | 0.79 | CHRM2 (0.54) | CHRM2CHRM1CHRM3ADRB2PTGER1 | |
| SCHEMBL6937177 | 0.76 | CHRM2 (0.56) | CHRM2CHRM1CHRM3ADRB2LMNA | |
| SCHEMBL6937179 | 0.76 | CHRM2 (0.56) | CHRM2CHRM1CHRM3ADRB2LMNA | |
| SCHEMBL12856745 | 0.76 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ADRB2LMNA | |
| SCHEMBL5178098 | 0.76 | CHRM2 (0.59) | CHRM2CHRM1CHRM3ADRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667852-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994011337-A9 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | — | 1995-07-06 | — | — | WO | disclosed |
| WO-1994011337-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 1994-05-26 | — | — | WO | disclosed |