Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.63 |
| ▸ | HPGD | P15428 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9212023 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL6589320 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9220473 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9220773 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL9212185 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9220110 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9220112 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9217370 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL24045243 | 0.79 | MEN1 (0.66) | KMT2AMEN1DUSP3PTPN5PTPN11 | |
| SCHEMBL9209085 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |