Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219789 | 0.83 | NPSR1 (0.41) | NPSR1GAAMAPT | |
| SCHEMBL9218601 | 0.81 | GRIN1 (0.33) | LMNA | |
| SCHEMBL7462560 | 0.76 | MAPT (0.41) | NPSR1GAALMNAMAPTTP53 | |
| SCHEMBL9219229 | 0.72 | NPSR1 (0.43) | NPSR1GAAMAPT | |
| SCHEMBL9212742 | 0.71 | NPSR1 (0.41) | NPSR1GAAMAPT | |
| SCHEMBL9221928 | 0.71 | MAPT (0.34) | NPSR1GAARAB9ALMNAMEN1 | |
| SCHEMBL7471256 | 0.70 | NPSR1 (0.43) | NPSR1GAALMNAMEN1MAPT | |
| SCHEMBL9215077 | 0.69 | NPSR1 (0.41) | NPSR1TSHRGAAMEN1MAPT | |
| SCHEMBL9212224 | 0.68 | HCRTR2 (0.32) | GAALMNAHSD17B10MEN1MAPT | |
| SCHEMBL9217235 | 0.68 | NPSR1 (0.35) | NPSR1TSHRGAAMAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |