⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940833 | 0.77 | HRH4 (0.38) | — | |
| SCHEMBL13406456 | 0.75 | GBA1 (0.40) | — | |
| SCHEMBL19024097 | 0.71 | — | — | |
| SCHEMBL363546 | 0.70 | — | — | |
| SCHEMBL4671779 | 0.69 | — | — | |
| SCHEMBL7145755 | 0.68 | POLB (0.31) | — | |
| SCHEMBL1680245 | 0.65 | — | — | |
| SCHEMBL1121814 | 0.65 | — | — | |
| SCHEMBL5318623 | 0.64 | — | — | |
| SCHEMBL8535533 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677039-A1 | CYCLOBUTANE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | Abbott Laboratories (US) | 1995-10-18 | — | — | EP | disclosed |