Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 15/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865702 | 0.72 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL7389176 | 0.72 | CYP19A1 (0.47) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL7391276 | 0.69 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL13105237 | 0.68 | CYP11B1 (0.72) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL31408151 | 0.68 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL2716739 | 0.68 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL7390725 | 0.66 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL30523908 | 0.66 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL15179016 | 0.66 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL30523909 | 0.66 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1TBXAS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492178-B1 | Naphthoic acid derivative | FUJIREBIO KK (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5324728-A | Lipoxygenase inhibiting antiallergens | FUJIREBIO INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0492178-A2 | Naphthoic acid derivative | FUJIREBIO INC. (JP) | 1992-07-01 | — | — | EP | disclosed |