Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546763 | 1.00 | AR (0.64) | ARKCNH2SRD5A2 | |
| SCHEMBL4802560 | 0.93 | AR (0.62) | ARKCNH2SRD5A2 | |
| SCHEMBL2639740 | 0.93 | AR (0.62) | ARKCNH2SRD5A2 | |
| SCHEMBL9272184 | 0.90 | AR (0.57) | ARKCNH2SRD5A2 | |
| SCHEMBL9546711 | 0.90 | AR (0.57) | ARKCNH2SRD5A2 | |
| SCHEMBL2639190 | 0.90 | AR (0.66) | ARKCNH2SRD5A2 | |
| SCHEMBL3862554 | 0.90 | AR (0.66) | ARKCNH2SRD5A2 | |
| SCHEMBL8902475 | 0.89 | AR (0.60) | ARKCNH2SRD5A2 | |
| SCHEMBL8902480 | 0.89 | AR (0.60) | ARKCNH2SRD5A2 | |
| SCHEMBL4802369 | 0.89 | AR (0.64) | ARKCNH2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649431-A4 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5-G(A)-REDUCTASE INHIBITORS. | — | 1995-05-03 | — | — | EP | claimed |
| EP-0649431-A1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5$g(a)-REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1995-04-26 | — | — | EP | claimed |
| WO-1993023038-A1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |