Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.53 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225206 | 1.00 | TP53 (0.54) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9330072 | 0.96 | RARB (0.57) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8378127 | 0.94 | TP53 (0.59) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8378126 | 0.94 | TP53 (0.59) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL6925756 | 0.94 | TP53 (0.59) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL28577854 | 0.90 | TP53 (0.49) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9328621 | 0.90 | RARB (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8606866 | 0.90 | RARB (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9327798 | 0.90 | RARB (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9328627 | 0.90 | RARB (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459134-A | Leukotriene antagonists; phospholipase, 5-alpha-reductase, and aldose reductase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| US-5446058-A | Leukotriene antagonists, 5-alpha-reductase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0173516-B1 | (Fused)benz(thio)amides | ONO PHARMACEUTICAL CO (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-4939141-A | (Fused) benz (thio) amides and pharmaceutical compositions, thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| US-4847275-A | ENZYME INHIBITOR, LEUKOTRIENE ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-07-11 | — | — | US | disclosed |
| US-4780469-A | (Fused) benz(thio)amides and pharmaceutical use | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-10-25 | — | — | US | disclosed |
| EP-0173516-A2 | (Fused)benz(thio)amides | ONO PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |