Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225263 | 0.96 | NPSR1 (0.52) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9230357 | 0.96 | NPSR1 (0.52) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9229514 | 0.92 | NPSR1 (0.61) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9226991 | 0.92 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9228137 | 0.92 | NPSR1 (0.59) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9224966 | 0.92 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9229584 | 0.92 | NPSR1 (0.48) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9231107 | 0.91 | NPSR1 (0.47) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9225345 | 0.88 | NPSR1 (0.45) | NPSR1KDM4EALDH1A1LMNASLC5A1 | |
| SCHEMBL9228112 | 0.88 | NPSR1 (0.58) | NPSR1KDM4EALDH1A1LMNAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | claimed |
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | disclosed |