Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526293 | 0.81 | MAPK1 (0.41) | MAPK1NR1H2NR1H3ALDH1A1TAAR1 | |
| SCHEMBL988384 | 0.77 | NR1H2 (0.48) | MAPK1NR1H2NR1H3ALDH1A1TAAR1 | |
| SCHEMBL9745411 | 0.73 | MAPK1 (0.42) | MAPK1NR1H2NR1H3ALDH1A1TAAR1 | |
| SCHEMBL25798859 | 0.71 | MAPK1 (0.41) | MAPK1NR1H2NR1H3ALDH1A1TAAR1 | |
| SCHEMBL29054459 | 0.70 | NR1H2 (0.45) | NR1H2NR1H3ALDH1A1ESR1ESR2 | |
| SCHEMBL6226453 | 0.70 | MAPK1 (0.39) | MAPK1NR1H2NR1H3ALDH1A1TAAR1 | |
| SCHEMBL21465431 | 0.70 | NR1H2 (0.46) | MAPK1NR1H2NR1H3ALDH1A1ESR1 | |
| SCHEMBL10628311 | 0.68 | ESR1 (0.43) | MAPK1NR1H2NR1H3ALDH1A1TAAR1 | |
| SCHEMBL6931682 | 0.68 | NR1H2 (0.44) | NR1H2NR1H3ALDH1A1ESR1ESR2 | |
| SCHEMBL7147500 | 0.68 | ESR1 (0.38) | NR1H2NR1H3ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378430-B1 | Novel organosilicon compound and process for producing organosilicon compound | AGENCY IND SCIENCE TECHN (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-5151538-A | ORGANOSILICON COMPOUND AND PROCESS FOR PRODUCING ORGANOSILICON COMPOUND | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0378430-A1 | Novel organosilicon compound and process for producing organosilicon compound | DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1990-07-18 | — | — | EP | disclosed |