SCHEMBL9226507

SCHEMBL9226507

CC[Si](C)(C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.45
ESR1 P03372 2/20 0.41
ESR2 Q92731 1/20 0.41
TP53 P04637 1/20 0.39
NR1H2 P55055 3/20 0.36
NR1H3 Q13133 3/20 0.36
MGAM O43451 2/20 0.35
TSHR P16473 1/20 0.33
PSIP1 O75475 1/20 0.33
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14369584 0.85 ESR1 (0.42) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL12191013 0.83 ESR1 (0.41) MAPTESR1ESR2TP53NR1H2
SCHEMBL9217667 0.80 MAPT (0.47) MAPTESR1ESR2TP53NR1H2
SCHEMBL12879487 0.79 MAPT (0.42) MAPTESR1ESR2TP53NR1H2
SCHEMBL15857807 0.79 NR1H2 (0.33) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL2329848 0.78 NR1H2 (0.47) MAPTESR1ESR2TP53NR1H2
SCHEMBL17721362 0.78 NR1H2 (0.38) MAPTESR1ESR2NR1H2NR1H3
Water SCHEMBL28197942 0.77 MAPT (0.41) MAPTESR1ESR2TP53NR1H2
SCHEMBL988676 0.77 NR1H2 (0.43) MAPTESR1ESR2TP53NR1H2
Sorbic Acid SCHEMBL28861239 0.76 MAPT (0.49) MAPTESR1ESR2PTGS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200112057-A1 ALKALI ION CONDUCTING PLASTIC CRYSTALS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-04-09 US claimed
US-20190020060-A1 ALKALI ION CONDUCTING PLASTIC CRYSTALS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2019-01-17 US claimed
CN-101074240-B Synthesis of P-bi(dimethyl-ethyl-silicone) benzene by sodium condensation HUAYE MEDICAL CHEMICAL CO LTD YANCHENG 2010-12-22 CN claimed
CN-101074240-A Synthesis of P-bi(dimethyl-ethyl-silicone) benzene by sodium condensation HUAYE MEDICAL CHEMICAL CO LTD (CN) 2007-11-21 CN claimed
US-12100804-B2 Alkali ION conducting plastic crystals ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-09-24 US disclosed
US-20240120532-A1 Alkali ION Conducting Plastic Crystals ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-04-11 US disclosed
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-06 US disclosed
US-11695153-B2 Alkali ion conducting plastic crystals ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-07-04 US disclosed
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20220123360-A1 ALKALI ION CONDUCTING PLASTIC CRYSTALS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2022-04-21 US disclosed
US-11094963-B2 Alkali ion conducting plastic crystals ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-08-17 US disclosed
CN-111033862-A Method for inhibiting decomposition of silyl ester compound 株式会社艾迪科 2020-04-17 CN disclosed
EP-0320211-B1 PROCESS FOR PRODUCING A TETRACARBOXYLIC ACID ANHYDRIDE HAVING DISILOXANE LINKAGE Hitachi Chemical Co., Ltd. (JP) 1993-06-16 EP disclosed
US-5166363-A Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1992-11-24 US disclosed
US-5151538-A ORGANOSILICON COMPOUND AND PROCESS FOR PRODUCING ORGANOSILICON COMPOUND AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1992-09-29 US disclosed
EP-0473658-A1 THERMAL INSULATION F. WILLICH GMBH &CO.. (DE) 1992-03-11 EP disclosed
WO-1990014553-A1 THERMAL INSULATION F. WILLICH GMBH & CO. (DE) 1990-11-29 WO disclosed
EP-0378430-A1 Novel organosilicon compound and process for producing organosilicon compound DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-07-18 EP disclosed
EP-0320211-A2 Process for producing a tetracarboxylic acid anhydride having disiloxane linkage Hitachi Chemical Co., Ltd. (JP) 1989-06-14 EP disclosed
EP-0292260-A2 Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof Hitachi Chemical Co., Ltd. (JP) 1988-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OTC, OCIAD1 MAPT 803/4885ESR1 465/4885ESR2 521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.