Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.95 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227895 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9228523 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL7217913 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL18585384 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9227926 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL18585372 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL6406 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL10335266 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL21580532 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9232100 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002682-A | Bleach compositions, their manufacture and use in bleach and laundry compositions | THE PROCTER & GAMBLE COMPANY (US) | 1991-03-26 | — | — | US | claimed |
| EP-0124341-B1 | BLEACH AUXILIARIES, THEIR MANUFACTURE AND USE IN BLEACH AND LAUNDRY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1990-07-25 | — | — | EP | claimed |
| EP-0124341-A2 | Bleach auxiliaries, their manufacture and use in bleach and laundry compositions | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-07 | — | — | EP | claimed |
| US-5419854-A | Electrochromic devices | YOSHIDA KOGYO K.K. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0603793-A2 | Organic solid electrolyte and coloring-discoloring device using the same | YKK CORPORATION (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5002682-A | Bleach compositions, their manufacture and use in bleach and laundry compositions | THE PROCTER & GAMBLE COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0124341-B1 | BLEACH AUXILIARIES, THEIR MANUFACTURE AND USE IN BLEACH AND LAUNDRY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| EP-0124341-A2 | Bleach auxiliaries, their manufacture and use in bleach and laundry compositions | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-07 | — | — | EP | disclosed |