Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988536 | 0.87 | CYP1A2 (0.49) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL31400240 | 0.87 | CYP1A2 (0.49) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL13311187 | 0.86 | CCR1 (0.64) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL29660049 | 0.86 | CCR1 (0.64) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL2007559 | 0.86 | CCR1 (0.64) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL16215309 | 0.84 | CCR1 (0.58) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL18489879 | 0.84 | CCR1 (0.62) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL13286613 | 0.84 | CCR1 (0.50) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL4812728 | 0.84 | CCR1 (0.50) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL15061960 | 0.84 | CCR1 (0.50) | CCR1CCR5CCR8KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411053-B2 | Ligand-functionalized/azo compounds and methods of use thereof | HARRUNA ISSIFU I | 2008-08-12 | — | — | US | disclosed |
| US-7411053-B2 | Ligand-functionalized/azo compounds and methods of use thereof | HARRUNA ISSIFU I | 2008-08-12 | — | — | US | disclosed |
| US-20070276104-A1 | LIGAND-FUNCTIONALIZED/AZO COMPOUNDS AND METHODS OF USE THEREOF | HARRUNA ISSIFU I | 2007-11-29 | — | — | US | disclosed |
| US-20070276104-A1 | LIGAND-FUNCTIONALIZED/AZO COMPOUNDS AND METHODS OF USE THEREOF | HARRUNA ISSIFU I | 2007-11-29 | — | — | US | disclosed |
| EP-0677293-A1 | PHARMACEUTICAL USE OF TERPYRIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276104-A1 | LIGAND-FUNCTIONALIZED/AZO COMPOUNDS AND METHODS OF USE THEREOF | FLT3, ALK, NECTIN4 | CCR1 204/4885CCR5 210/4885CCR8 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.