Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717768 | 1.00 | ECE1 (0.44) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8717867 | 1.00 | ECE1 (0.44) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8427315 | 0.99 | ECE1 (0.45) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL901315 | 0.97 | ECE1 (0.44) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8720265 | 0.97 | ECE1 (0.44) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8717807 | 0.97 | ECE1 (0.44) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9389801 | 0.97 | ECE1 (0.46) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8422216 | 0.97 | ECE1 (0.43) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8344856 | 0.97 | ECE1 (0.43) | ECE1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL5435922 | 0.97 | ECE1 (0.43) | ECE1MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457046-A | Polypeptides | NOVO NORDISK A/S (DK) | 1995-10-10 | — | — | US | disclosed |