Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233898 | 0.91 | MEN1 (0.44) | KDM4EKMT2AMEN1ADRA2BMAPK1 | |
| SCHEMBL9234131 | 0.90 | PIM1 (0.39) | KDM4EKMT2AMEN1PIM1GSK3A | |
| SCHEMBL9233550 | 0.90 | KMT2A (0.46) | KDM4EKMT2APIM1GSK3AGSK3B | |
| SCHEMBL9673019 | 0.89 | KDM4E (0.46) | KDM4EKMT2AMEN1PIM1GSK3A | |
| SCHEMBL9232084 | 0.88 | KDM4E (0.55) | KDM4EPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL9229134 | 0.88 | PIM1 (0.36) | KDM4EKMT2AMEN1PIM1GSK3A | |
| SCHEMBL9231592 | 0.87 | STAT3 (0.42) | KDM4EKMT2APIM1GSK3AGSK3B | |
| SCHEMBL9233962 | 0.86 | PIM1 (0.40) | KDM4EKMT2AMEN1PIM1GSK3A | |
| SCHEMBL9233957 | 0.86 | PIM1 (0.40) | KDM4EKMT2AMEN1PIM1GSK3A | |
| SCHEMBL9791232 | 0.85 | KMT2A (0.45) | KDM4EKMT2AMEN1PIM1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675127-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |