Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TOP2A | P11388 | 4/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235745 | 0.93 | KDM4E (0.46) | KDM4ETOP2ATOP1POLBCACNA1F | |
| SCHEMBL9233837 | 0.91 | KDM4E (0.54) | KDM4ETOP2ATOP1POLBCACNA1F | |
| SCHEMBL9232505 | 0.90 | KDM4E (0.44) | KDM4ETOP2ATOP1POLBCACNA1F | |
| SCHEMBL9234604 | 0.89 | KCNH2 (0.41) | KDM4EPOLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9233183 | 0.88 | KDM4E (0.45) | KDM4ETOP2ATOP1POLBCACNA1F | |
| SCHEMBL9234627 | 0.86 | CACNA1F (0.51) | KDM4EPOLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9228918 | 0.85 | KDM4E (0.40) | KDM4ETOP2ATOP1POLBCACNA1F | |
| SCHEMBL9232358 | 0.85 | KDM4E (0.40) | KDM4EPOLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL8134319 | 0.85 | KDM4E (0.40) | KDM4ETOP2APOLBCACNA1FMAPK1 | |
| SCHEMBL8202150 | 0.82 | KDM4E (0.43) | KDM4EPOLBCACNA1FMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683169-A1 | 8-Amino-pyrido 1,2,3-de 1,3,4 benzoxadiazine derivatives, and antibacterial agents containing them | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |