Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.65 |
| ▸ | HRH1 | P35367 | 5/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223145 | 0.87 | HTR2A (0.47) | HTR2AHRH1MEN1KMT2AIDO1 | |
| SCHEMBL8858816 | 0.84 | CHRM2 (0.55) | HTR2AHRH1CHRM2SLC6A4MEN1 | |
| SCHEMBL11291158 | 0.82 | IDO1 (0.55) | HTR2AHRH1SLC6A2SLC6A4MEN1 | |
| SCHEMBL6330054 | 0.81 | MEN1 (0.51) | SLC6A2SLC6A4MEN1KMT2AIDO1 | |
| Ammonia Solution, Strong SCHEMBL6001490 | 0.80 | IDO1 (0.53) | HTR2AHRH1SLC6A2SLC6A4MEN1 | |
| SCHEMBL9226280 | 0.80 | MEN1 (0.44) | HTR2AHRH1MEN1KMT2AIDO1 | |
| SCHEMBL1802493 | 0.80 | HRH1 (1.00) | HTR2AHRH1CHRM2SLC6A2SLC6A4 | |
| SCHEMBL6001484 | 0.79 | HRH1 (0.59) | HTR2AHRH1SLC6A2SLC6A4MEN1 | |
| SCHEMBL11387106 | 0.79 | MEN1 (0.50) | SLC6A2SLC6A4MEN1KMT2AIDO1 | |
| SCHEMBL4938883 | 0.79 | MEN1 (0.50) | SLC6A2SLC6A4MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382600-A | 3,3-diphenylpropylamines and pharmaceutical compositions thereof | PHARMACIA AKTIEBOLAG (SE) | 1995-01-17 | — | — | US | disclosed |
| EP-0325571-B1 | NEW AMINES, THEIR USE AND PREPARATION | Kabi Pharmacia AB (SE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0354234-A1 | NEW AMINES, THEIR USE AND PREPARATION | KabiVitrum AB (SE) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989006644-A1 | NEW AMINES, THEIR USE AND PREPARATION | KABIVITRUM AB (SE) | 1989-07-27 | — | — | WO | disclosed |
| EP-0325571-A1 | New amines, their use and preparation | Kabi Pharmacia AB (SE) | 1989-07-26 | — | — | EP | disclosed |