Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 10/20 | 0.68 |
| ▸ | NPFFR2 | Q9Y5X5 | 10/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2348786 | 0.84 | NPFFR1 (0.64) | NPFFR1NPFFR2SIGMAR1IDO1CYP2D6 | |
| SCHEMBL14728238 | 0.84 | NPFFR1 (0.64) | NPFFR1NPFFR2SIGMAR1IDO1CYP2D6 | |
| SCHEMBL13320953 | 0.82 | NPFFR1 (0.62) | NPFFR1NPFFR2SIGMAR1DRD2 | |
| SCHEMBL6635524 | 0.82 | NPFFR1 (0.62) | NPFFR1NPFFR2SIGMAR1OPRK1IDO1 | |
| SCHEMBL22050090 | 0.82 | NPFFR1 (0.62) | NPFFR1NPFFR2SIGMAR1IDO1CYP2D6 | |
| SCHEMBL23070812 | 0.80 | NPFFR1 (0.60) | NPFFR1NPFFR2SIGMAR1 | |
| SCHEMBL16926455 | 0.80 | NPFFR1 (0.60) | NPFFR1NPFFR2SIGMAR1OPRK1 | |
| SCHEMBL4511211 | 0.80 | NPFFR1 (0.59) | NPFFR1NPFFR2SIGMAR1IDO1CYP2D6 | |
| SCHEMBL23268368 | 0.80 | NPFFR1 (0.59) | NPFFR1NPFFR2SIGMAR1IDO1CYP2D6 | |
| SCHEMBL2281940 | 0.80 | NPFFR1 (0.59) | NPFFR1NPFFR2SIGMAR1IDO1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |