Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226808 | 0.84 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| Ammonia Solution, Strong SCHEMBL7591982 | 0.81 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL9232610 | 0.79 | GRIN2D (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL9233161 | 0.76 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7564476 | 0.75 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8638991 | 0.71 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8086902 | 0.67 | GRIN1 (0.55) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8090253 | 0.67 | — | — | |
| Bromide SCHEMBL8085949 | 0.65 | GRIN1 (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9226819 | 0.64 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040649-A1 | AMINO ACID DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |