Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682678 | 0.90 | MEN1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10680080 | 0.87 | CACNA1F (0.50) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL8852040 | 0.86 | MEN1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9231288 | 0.85 | POLB (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL10683428 | 0.84 | MEN1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9233385 | 0.84 | MEN1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL8327191 | 0.83 | MEN1 (0.37) | ALDH1A1MEN1KMT2AKCNH2POLB | |
| SCHEMBL10685467 | 0.82 | CACNA1F (0.47) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10685697 | 0.80 | MEN1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10679847 | 0.80 | MEN1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671391-A1 | 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids | BAYER AG (DE) | 1995-09-13 | — | — | EP | disclosed |