SCHEMBL9235490

SCHEMBL9235490

Nc1nc2nc(Cc3ccccc3F)[nH]c2c(=O)[nH]1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNP P00491 7/20 0.67
FGFR1 P11362 1/20 0.50
FGFR2 P21802 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1938287 0.86 PNP (0.71) PNPFGFR1FGFR2
SCHEMBL1935857 0.85 PNP (0.69) PNPFGFR1FGFR2
SCHEMBL9434929 0.84 PNP (0.71) PNPFGFR1FGFR2
Hydrochloric Acid SCHEMBL17186418 0.84 PNP (0.67) PNPFGFR1FGFR2
SCHEMBL3304327 0.84 PNP (0.60) PNPFGFR1FGFR2
SCHEMBL9283418 0.83 PNP (0.66) PNPFGFR1FGFR2
SCHEMBL17186524 0.83 PNP (0.55) PNP
SCHEMBL17186379 0.83 PNP (0.58) PNPFGFR1FGFR2
Hydrochloric Acid SCHEMBL17186451 0.82 PNP (0.57) PNPFGFR1FGFR2
Hydrochloric Acid SCHEMBL17186366 0.82 PNP (0.54) PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7267955-A None JP disclosed
JP-H07267955-A BENZYLGUANINE DERIVATIVE TOAGOSEI CO LTD 1995-10-17 JP disclosed