Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356103 | 0.86 | RARB (0.68) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9236012 | 0.85 | RARB (0.50) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL8532765 | 0.83 | RARB (0.74) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9745002 | 0.83 | RARB (0.74) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9733624 | 0.83 | RARB (0.74) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL8943378 | 0.83 | RARB (0.74) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9745065 | 0.83 | RARB (0.74) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9238965 | 0.83 | RARB (0.72) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL9745273 | 0.82 | RARB (0.72) | RARBSMN1; SMN2NPC1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL9744738 | 0.82 | RARB (0.72) | RARBSMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389290-A | Ferroelectric liquid crystalline materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5089168-A | Stable ferroelectric liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4834904-A | FERROELECTRIC LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |